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For Researchers

Health Research Authority (HRA) Approval

The Health Research Authority (HRA) works on behalf of NHS Trusts in England and in conjunction with the NHS Research Ethics Committee (REC).  Their duty is to ensure that clinical research conducted within the health service adheres to strict ethical, legal and governance guidelines in order to ensure the safety and dignity of our patients and the integrity of the Trust.

If you wish to conduct clinical research with the Trust you will need to apply for HRA Approval.

Use the Integrated Research Application System (IRAS) to make the necessary regulatory applications

The dataset that is entered into this system can be used for most of the necessary regulatory applications (e.g. REC/HRA/MHRA). 

It is important to ensure that when you create your new project that you consider and answer the filter questions carefully as the responses to these will generate the specific form(s) required to be completed.  An incorrect response here will mean that the applications created are not accepted as valid and will result in delay for the applicant.  For guidance please contact the Research Adviser.

The Health Research Authority (HRA) website contains all the necessary guidance and information required to make these applications

For further information on the HRA please visit or download our HRA Approvals training slides

For further information on HRA and REC Approval please visit:

1st April 2020 to 31st March 2021

York and Scarborough

100 research studies open to recruitment


4760 patients recruited into clinical trials